Practice Question Bank

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Our Practice Question Bank includes the largest collection of MCAT practice questions available, covering ALL the MCAT concepts officially outlined by the AAMC. Our full collection includes over 5,000 carefully crafted flashcards and more than 2,500 AAMC-style standalone quiz questions. It’s been a very helpful study aid to my students, several of whom have scored in the 100th percentile. I am confident it will help you too.



Quiz Questions

Our 120 End-of-Lesson Mastery Quizzes feature 2,500+ AAMC-style standalone questions to test your learning on every lesson taught in the content modules.

Every quiz question comes complete with answer explanations, worked math solutions, pictures, and diagrams. You can review and retake quizes anytime.

Try an End-of-Lesson Quiz!


Lesson 1: Amino Acids and Proteins

Amino Acids and Proteins

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A new protein has been discovered in the bottom of the ocean. Researchers want to predict the folding patterns of the protein. Which of the following will the researchers most likely analyze for these predictions?

2 / 24

A food scientist researches a new way to cook eggs. Which of the following methods will effectively denature the primary structure of egg proteins? 

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3 / 24

Due to their greater stability, antiparallel beta sheets tend to withstand greater physical and solvent-induced distortions than their parallel counterparts. This can be attributed to the fact that the polymers in an antiparallel beta pleated sheet run in ____ directions and polymers in a parallel beta pleated sheet run in the ____ directions.

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4 / 24

Cysteine has a thiol group as part of its side chain. Why does cysteine preferentially form disulfide bonds in the extracellular environment?

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5 / 24

A researcher studies the properties of amino acids at different pH levels. If the pH is equal to the pKa of the amino acid in beaker 1, which of the following is true regarding the amino acid?

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6 / 24

A patient with a consistent blood glucose level greater than 300 mg/dL is determined to be in diabetic ketoacidosis (DKA). DKA patients typically have a pH below 7.4. Which of the following amino acids would not be protonated when pH falls below 6.25?

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7 / 24

A researcher investigates one mechanism of protein folding and solvation layer formation. The protein studied is rich in phenylalanine and leucine amino acids. When the protein is submerged in an aqueous solution, the water molecules in the solvation layer cannot form hydrogen bonds with the protein's side chain. What will most likely result from the occurrence of this phenomenon?

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8 / 24

Given that a protein is composed of nonpolar amino acids and displays typical patterns of protonation/deprotonation for neutral amino acids, which of the following amino acids is this protein most likely composed of?

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9 / 24

A researcher works with a protein composed of nonpolar amino acids that is found in human blood. The researcher studies the behavior of amino acids within the protein after exposure to different conditions.

Condition 1: pH = 2

Condition 2: pH = 10

Condition 3: pH = 6.8

Which of the following is true?

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10 / 24

Researchers have identified a certain prion that causes the human protein abc to misfold by affecting α-helices. When a cell is infected by this particular prion, what most likely happens to protein abc at the molecular level?

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11 / 24

A researcher is able to denature a protein by adding it to a solution with low pH. Which of the following bonds is not broken in this solution?

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12 / 24

Vacuum ultraviolet circular dichroism is an experimental technique used to identify β-turns in polypeptide chains. Which of the following correctly describes the location and content of β-turns?

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13 / 24

Keratins are structural proteins integral to the vertebrate epidermis. The secondary structure of keratin is largely composed of α-helices. A majority of these α-helices are:

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14 / 24

Ser108 and Gln114 are residues in the same α-helix of an antibody. A hydrogen bond:

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15 / 24

What is the correct amino acid sequence for this polypeptide? (See image)

Question Image

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16 / 24

High levels of cyclin-dependent kinase activity have been implicated in tumorigenesis. Which of the following amino acids' R groups would likely remain unchanged in the presence of a kinase?

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17 / 24

A scientist shines plane polarized light through various amino acids. Which amino acid will not show optical activity?

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18 / 24

The amino acid histidine is often found in the active site of several enzymes. Which of the following best explains why this is true?

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19 / 24

Zwitterions are amphoteric, meaning that they can act as both acids and bases. At what pH are amino acids predominantly in their Zwitterion form?

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20 / 24

A researcher wishes to introduce a mutation to an enzyme that utilizes Threonine to bind reactants in its active site. Which of the following amino acids would replace threonine in such a way to inhibit the activity of the enzyme?

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21 / 24

A certain protein is 8 amino acids in length. How many different amino acid sequences are possible for this protein?

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22 / 24

An unspecified virus uses RNA as its genetic material. This viral RNA could possibly lead to the synthesis of which of the following?



III. Proteins

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23 / 24

The Strecker synthesis is often conducted to produce racemic mixtures of methionine. Which of the following is not a starting component for the Strecker synthesis?

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Gabriel synthesis is often used in the preparation of primary aromatic amines, which can be used as a starting material in the manufacture of dyes. What type of reaction occurs in Gabriel synthesis?

Your score is

The average score is 62%




Our Quizlet flashcards comprehensively cover every single concept taught by Khan Academy and several content review books.

Each carefully crafted flashcard comes complete with answer explanations, worked math solutions, pictures, diagrams, as well as AAMC-style stand-alone questions. You can star notecards for future review, click to zoom in on pictures, and even study on the go using the Quizlet mobile app.

Click on “options,” then select “answer with definition” to give it a try!

Why Students Love Our Practice Question Bank



Our Practice Question Bank comprehensively covers every single concept taught by Khan Academy and several content review books.



Creating your own notecards for every single concept is extremely time-consuming. Studying with our Practice Question Bank is a huge time-saver!


Students love how each practice question set and flashcard collection is matched with an associated Khan Academy playlist and Kaplan/Princeton Review reading assignment.



With mobile friendly content modules and the free Quizlet mobile app, you can study our practice questions anywhere, anytime. Busy pre-meds love being able to study on the go!


Actively engaging with MCAT content through practice is the very best way to improve. Students love how much faster they learn with our Practice Question Bank.



Peace of mind comes from knowing you’ve mastered every single MCAT concept you need to know. With our Practice Question Bank, no concept is left behind.


Double Check Understanding

After watching Khan Academy videos or reading the content review books, students love using our Flashcards and End-of-Lesson Mastery Quizzes to confirm that they learned everything within each content module.

Save Time

It is extremely time-consuming to find content-specific practice questions based on the concepts you are currently learning. Students use our Practice Question Bank to practice concepts immediately, saving precious study time.

Last Minute Comprehensive Review

Students love using our Practice Question Bank during their final period of MCAT studying as a method for quickly reviewing every piece of MCAT content needed to succeed on test day.

Students Love our Practice Question Bank


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“If anyone is planning on taking the MCAT, I recommend using MCAT Self Prep; it has awesome resources and tutors who go above and beyond for you.” Read more.

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“After spending 4K+ on a MCAT testing company on my first attempt, I retook the MCAT with Andrew. The website/system that Andrew offers is the utopia of MCAT preparation. Not only does it prepare you for the MCAT but also, changes your lifestyle and how one should properly approach the MCAT. During the diagnostics & taking FLs, my score changed from a 495 to a 510 and I witnessed a 7 point increase on the real deal. With the great great great great FLASHCARDS that I was able to use anywhere, I got the MCAT score I wanted. HIGHLY RECOMMEND. Thank you Andrew for all your work.”
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“One of the things that really stood out to me was Andrew’s emphasis on high quality note cards as well as his program’s affordability compared to other companies. On test day, I got a 514 with a perfect score in Behavioral Sciences. It’s been my experience that using note cards is the best study method for the MCAT, as most of the questions are looking for you to apply small pieces of memorized information to different situations. I definitely felt over-prepared on test day. You can’t find a more concise yet comprehensive set of note cards for this massive test than Andrew and his materials!
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“As a 30 year-old non-traditional applicant, I had to find every topic covered on the MCAT and then re-teach it to myself. Andrew’s course was a great way to do that. The main course is free, but I did purchase the Practice Question Bank and a few other courses (Math, 100 Equations, Amino Acids). All of the information I learned was invaluable to my success on the exam and admittance into medical school. I highly recommend the use of this resource. Everything is straightforward and there were no issues with any unnecessary charges.”


The full Practice Question Bank is available as part of MCAT Self Prep’s Advanced Pro Plan for just $199.99!

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Access to over 5,000 Quizlet Flaschards that cover every single concept taught by Khan Academy and several content review books.

Access to 120 End-of-Lesson Mastery Quizzes, featuring 2,500+ AAMC-style standalone questions.

Create-your-own Study Plan Course, which includes our Create-your-own Study Plan Spreadsheet, Study Portal, and Score Tracker.

Full MCAT Video Collection, which covers ALL the MCAT topics as listed by the AAMC.

All ten content modules (Biology I, Physics II, etc) as well as MCAT Bootcamp with customization.

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Want help with more than just content mastery?

Our Deluxe Pro Plan includes access to our full Practice Question Bank plus every other mastery course and product on our site, including Ultimate CARS Strategy Course, Science Passage Reading Strategy Course, and Medical School Application Course. Separately, these courses would cost you over $2,500. Bundled as part of the Deluxe Pro Plan, however, you can have it all for just $1,399.

Frequently Asked Questions

Which plan is right for me?

If you are not sure which plan is right for you, simply request a free consultation with Andrew and he will point you in the right direction. He’s worked with hundreds of students and knows what you’ll need to achieve your goal in your unique situation.

If I am not currently using the MCAT Self Prep eCourse, will these practice questions help me?

Yes! The Flashcards are organized in the same way as our online eCourse, but they can be used in conjunction with any other study tool. They cover every single concept taught by Khan Academy as well as several content review books, so if you are looking for a way to quickly test yourself on every single MCAT concept, you will love our practice question bank.

Why should I upgrade from the Free Forever to the Advanced Pro Plan?

Although the Free Forever Plan and Basic Pro Plan provide you with the ability to try out 300 Flashcards (about 3 per lesson), and sample 120 mini-Quizzes (3 questions per quiz), the Advanced Pro Plan will provide you with full access to all 5,000+ flashcards and 2,500+ AAMC-style practice questions integrated into each lesson. Students love using these practice questions to double-check their understanding of what they learned during each content module, do a rapid review of every single MCAT concept, or save them time from needing to make thousands of their own flashcards. Our Practice Question Bank is our most popular resource.

If I start with the Basic or Advanced Pro Plan first, will you reimburse me when I upgrade to the Deluxe Pro Plan later?

Yes! We are big believers in “try before you buy.” As soon as you sign up for either the Basic or the Advanced Pro Plans, we will provide you with a discount for the higher-tier plans equal to the value of your purchase. For instance, if you start with the Basic Pro for $19.99, you will automatically receive a $19.99 credit towards your purchase of the Advanced or Deluxe Pro Plans. If you start with the Advanced Pro Plan for $199.99, you will get a $199.99 credit towards your purchase of the Deluxe Pro Plan.

Who created these flashcards and practice questions?

Our Founder and Head Tutor, Andrew George wrote most of these flashcards and each one has been edited at least twice by one of our Elite Tutors.

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All our products are a one-time payment for lifetime access. 🙂 While other test prep companies have strict expiration dates for all of their plans and programs, we do not believe that is fair to you. You deserve to be able to access what you purchased until you have taken the MCAT and are satisfied with your score.

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Yes! Simply select affirm pay over time at checkout to customize your payment plan with affirm. In some cases, affirm can decline users from using their pay-over-time service. If this happens, you can shoot me a message, and we’ll get you set up with a personalized monthly payment plan that will suit your financial needs. If you have questions or need to make changes to your affirm payment plan, you can contact affirm here. For non-affirm, custom payment plans, contact us.

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We trust that you will not share our products with your friends, relatives, or even siblings. In return, we offer you our support and the lowest price out there. MCAT Self Prep is a family business, which provides a livelihood for those working hard to provide you with quality test prep. By offering students lifetime access to our pro plans, we run the risk that you will share your account with others, ruining our ability to make a living. Instead of having expiration dates for plans or implementing strict security protocols, we believe in having a relationship of trust with you. Please treat us with kindness and respect in return.

If you have a unique situation, have a lot of questions, or are looking for a confirmation that you are making the right purchase, you will likely benefit from consultation with our Head Tutor, Andrew George. He has worked one-on-one with hundreds of diverse students and will carefully consider your unique situation as he provides a careful recommendation and answers your questions.