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Lesson 1: Amino Acids and Proteins

Amino Acids and Proteins

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1 / 24

A new protein has been discovered in the bottom of the ocean. Researchers want to predict the folding patterns of the protein. Which of the following will the researchers most likely analyze for these predictions?

2 / 24

A food scientist researches a new way to cook eggs. Which of the following methods will effectively denature the primary structure of egg proteins? 

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3 / 24

Due to their greater stability, antiparallel beta sheets tend to withstand greater physical and solvent-induced distortions than their parallel counterparts. This can be attributed to the fact that the polymers in an antiparallel beta pleated sheet run in ____ directions and polymers in a parallel beta pleated sheet run in the ____ directions.

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4 / 24

Cysteine has a thiol group as part of its side chain. Why does cysteine preferentially form disulfide bonds in the extracellular environment?

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5 / 24

A researcher studies the properties of amino acids at different pH levels. If the pH is equal to the pKa of the amino acid in beaker 1, which of the following is true regarding the amino acid?

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6 / 24

A patient with a consistent blood glucose level greater than 300 mg/dL is determined to be in diabetic ketoacidosis (DKA). DKA patients typically have a pH below 7.4. Which of the following amino acids would not be protonated when pH falls below 6.25?

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7 / 24

A researcher investigates one mechanism of protein folding and solvation layer formation. The protein studied is rich in phenylalanine and leucine amino acids. When the protein is submerged in an aqueous solution, the water molecules in the solvation layer cannot form hydrogen bonds with the protein's side chain. What will most likely result from the occurrence of this phenomenon?

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8 / 24

Given that a protein is composed of nonpolar amino acids and displays typical patterns of protonation/deprotonation for neutral amino acids, which of the following amino acids is this protein most likely composed of?

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9 / 24

A researcher works with a protein composed of nonpolar amino acids that is found in human blood. The researcher studies the behavior of amino acids within the protein after exposure to different conditions.

Condition 1: pH = 2

Condition 2: pH = 10

Condition 3: pH = 6.8

Which of the following is true?

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10 / 24

Researchers have identified a certain prion that causes the human protein abc to misfold by affecting α-helices. When a cell is infected by this particular prion, what most likely happens to protein abc at the molecular level?

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11 / 24

A researcher is able to denature a protein by adding it to a solution with low pH. Which of the following bonds is not broken in this solution?

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12 / 24

Vacuum ultraviolet circular dichroism is an experimental technique used to identify β-turns in polypeptide chains. Which of the following correctly describes the location and content of β-turns?

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13 / 24

Keratins are structural proteins integral to the vertebrate epidermis. The secondary structure of keratin is largely composed of α-helices. A majority of these α-helices are:

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14 / 24

Ser108 and Gln114 are residues in the same α-helix of an antibody. A hydrogen bond:

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15 / 24

What is the correct amino acid sequence for this polypeptide? (See image)

Question Image

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16 / 24

High levels of cyclin-dependent kinase activity have been implicated in tumorigenesis. Which of the following amino acids' R groups would likely remain unchanged in the presence of a kinase?

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17 / 24

A scientist shines plane polarized light through various amino acids. Which amino acid will not show optical activity?

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18 / 24

The amino acid histidine is often found in the active site of several enzymes. Which of the following best explains why this is true?

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19 / 24

Zwitterions are amphoteric, meaning that they can act as both acids and bases. At what pH are amino acids predominantly in their Zwitterion form?

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20 / 24

A researcher wishes to introduce a mutation to an enzyme that utilizes Threonine to bind reactants in its active site. Which of the following amino acids would replace threonine in such a way to inhibit the activity of the enzyme?

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21 / 24

A certain protein is 8 amino acids in length. How many different amino acid sequences are possible for this protein?

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22 / 24

An unspecified virus uses RNA as its genetic material. This viral RNA could possibly lead to the synthesis of which of the following?

I. cDNA

II. mRNA

III. Proteins

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23 / 24

The Strecker synthesis is often conducted to produce racemic mixtures of methionine. Which of the following is not a starting component for the Strecker synthesis?

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24 / 24

Gabriel synthesis is often used in the preparation of primary aromatic amines, which can be used as a starting material in the manufacture of dyes. What type of reaction occurs in Gabriel synthesis?

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If you are not sure which plan is right for you, simply request a free consultation with Andrew and he will point you in the right direction. He’s worked with hundreds of students and knows what you’ll need to achieve your goal in your unique situation.

If I am not currently using the MCAT Self Prep eCourse, will these Quizlet Flashcards help me?

Yes! The Quizlet Flashcards are organized in the same way as our online eCourse, but they can be used in conjunction with any other study tool. They cover every single concept taught by Khan Academy as well as several content review books, so if you are looking for a way to quickly test yourself on every single MCAT concept, you will love our Quizlet Flashcards.

Why should I upgrade from the Free Forever Plan or Basic Pro Plan to the Advanced Pro Plan?

Although the Free Forever Plan and Basic Pro Plan provide you with the ability to try out 300 Flashcards (about 3 per lesson), and sample 120 mini-Quizzes (3 questions per quiz), the Advanced Pro Plan will provide you with full access to all 5,000+ flashcards and 2,500+ AAMC-style practice questions integrated into each lesson. Students love using these practice questions to double-check their understanding of what they learned during each content module, do a rapid review of every single MCAT concept, or save them time from needing to make thousands of their own flashcards. Our Practice Question Bank is our most popular resource.

If I start with the Basic or Advanced Pro Plan first, will you reimburse me when I upgrade to the Deluxe Pro Plan later?

Yes! We are big believers in “try before you buy.” As soon as you sign up for either the Basic or the Advanced Pro Plans, we will provide you with a discount for the higher-tier plans equal to the value of your purchase. For instance, if you start with the Basic Pro for $19.99, you will automatically receive a $19.99 credit towards your purchase of the Advanced or Deluxe Pro Plans. If you start with the Advanced Pro Plan for $199.99, you will get a $199.99 credit towards your purchase of the Deluxe Pro Plan.

Who created these flashcards?

Our Founder and Head Tutor, Andrew George wrote most of these flashcards and each one has been edited at least twice by one of our Elite Tutors.

When will my access expire?

All our products are a one-time payment for lifetime access. 🙂 While other test prep companies have strict expiration dates for all of their plans and programs, we do not believe that is fair to you. You deserve to be able to access what you purchased until you have taken the MCAT and are satisfied with your score.

Can I defer my payment or pay in increments over time?

Yes! Simply select affirm pay over time at checkout to customize your payment plan with affirm. In some cases, affirm can decline users from using their pay-over-time service. If this happens, you can shoot me a message, and we’ll get you set up with a personalized monthly payment plan that will suit your financial needs. If you have questions or need to make changes to your affirm payment plan, you can contact affirm here. For non-affirm, custom payment plans, contact us.

Can I share my account with a friend or relative?

We trust that you will not share our products with your friends, relatives, or even siblings. In return, we offer you our support and the lowest price out there. MCAT Self Prep is a family business, which provides a livelihood for those working hard to provide you with quality test prep. By offering students lifetime access to our pro plans, we run the risk that you will share your account with others, ruining our ability to make a living. Instead of having expiration dates for plans or implementing strict security protocols, we believe in having a relationship of trust with you. Please treat us with kindness and respect in return.

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How we Matched up the Khan Academy Passages with the eCourse Lessons

Each lesson of the eCourse contains links to 1 to 5 Khan Academy science passages for the purpose of providing you with non-AAMC material to practice your science passage reading skills on. By completing all the linked passages within every lesson, you will have finished all the freely available Khan Academy science passages.

To match up the Khan Academy Science Passages with the eCourse lessons, we carefully examined the passage and question content of each one. Then we decided which lesson of the eCourse best correlated with that content. You may notice that some passages don’t match up perfectly with the current lesson. If they don’t match up with the current lesson, they should match up with one of the previous lessons in the module. We did this carefully so that you could practice your science passage reading skills on passages that contain the content you’ve already learned.

Why we don’t recommend non-AAMC CARS practice questions

We recommend practicing CARS by reading non-AAMC CARS passages but not doing the associated practice problems. The reason we don’t recommend doing the practice problems is because the MCAT is written by the AAMC. They have a very unique style in which they write CARS practice questions that third-party companies (try as they might) are unable to replicate. When students spend time on non-AAMC CARS practice problems, they get familiar with the wrong style of questioning, leading them to overthink and incorrectly respond to the questions written by the AAMC. Thus, it is in your best interest to solely practice on AAMC CARS practice questions.

That said, we highly recommend practicing your reading skills on non-AAMC CARS passages. In our Ultimate CARS Strategy Course, we provide you with 1,000 free CARS passages and 100+ homework assignments, giving you ample material to practice on. Reading countless passages while practicing the proper reading habits and strategies will prepare you well to conquer the CARS section as it was written by the AAMC.

Which books do the lessons match up with?

The books we use in each lesson are linked below. We plan to stick with these older editions of the books since very little has changed and the older editions are much more affordable:

First Edition of the Kaplan 7-book Series
First Edition of the Princeton 7-book Series

Do the chapters match up perfectly?

The Kaplan Books, Princeton Books, and Khan Academy Videos were all produced by different authors. For this reason, there are some chapters in the Kaplan Book or Princeton Book that are not even found in the Khan Academy Videos and vice versa. For instance, the Kaplan and Princeton Books have chapters that cover certain experimental procedures that the Khan Academy Videos do not cover.

Our goal in matching up the books with the videos was to correlate the content as best as possible while also covering ALL the content from every resource. For this reason, when nothing in the Kaplan Books matched up with one of the video playlists, instead of leaving the reading assignment for Kaplan blank, we inserted material that did not fit in anywhere else (i.e. one of those chapters on an experimental procedure that was not covered by Khan Academy). So, when the assignment doesn’t appear to match up right, please know that this was intentional.

*If you follow the reading assignments outlined, you will finish the entire Kaplan 7-book series and/or Princeton 7-book series by the time you finish all 10 content modules.

Do the sections match up perfectly?

If the sections assigned in our eCourse do not match up with the sections contained in your content review book, you may have a different edition. The sections should still match up the large majority of the time, but in the rare instance that they don’t, I’d recommend simply reading sections that do match up and saving the ones that do not for a future lesson.

MCAT Launchpad Required!

Before jumping into our free eCourse, you’ll need to complete orientation by watching MCAT Launchpad. During this free 35-minute intro session with Head Tutor Andrew, you’ll learn 6 Keys to Earning a Top MCAT Score, the 5 Essential Elements of an Effective Study Plan, 12 Tips for Taking the Best MCAT Study Notes, and more! Andrew will also provide you with a detailed overview of the Free MCAT Prep Course, teaching you how to get started.

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